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St. Louis, MO (Population: 2,796,368)

St. Louis, Missouri, with a population of 2,796,368, is located on the Mississippi River. The city's many nicknames include "Mound City" and "The Gateway City." Once home to the Mississippi Mound Builders, as the Native Americans in the area were known, St. Louis became a part of the United States as a part of the Louisiana Purchase. St. Louis is known historically for hosting the 1904 World's Fair and the 1904 Olympic Games, which was the first time they had been held in the United States.

St. Louis is considered a center for the biotechnology and medical fields, largely due to the number of hospitals and universities in the area, such as the Washington University School of Medicine. Other institutions of higher learning located here include the University of Mississippi- St. Louis, St. Louis University, and Maryville University. In sports, the city is home to several major league teams, including the St. Louis Cardinals and the St. Louis Rams. Baseball fans have deemed St. Louis "Baseball City USA" and with good reason; the Cardinals have won ten World Series Championships, more than any other team besides the New York Yankees.

Forest Park is one of the largest urban parks in the world and is home to a zoo, an outdoor theatre and the St. Louis Science Center. The St. Louis Art Museum is also housed in Forest Park. Other St. Louis Parks, such as the Tower Grove Garden and the Missouri Botanical Garden are also well-established and popular attractions. In architecture the city has several famous churches and cathedrals in various architectural styles, such as the Cathedral Basilica of St. Louis, the Basilica of St. Louis, King of France and the Saint Louis Abbey. Grand Center, an arts institution which houses the Pulitzer Foundation for the Arts is also of architectural interest, having been built by famous architect Tadao Ando. Other attractions in St. Louis include the St. Louis Union Station, the Fox Theatre and the Gateway Arch- one of the city's most distinguishing features.